Crohn’s Disease Cure
Cure Crohns and Colitis have a simple mission – to find a cure for Crohn’s disease and other related forms of IBD – we’re already making amazing progress, but the next step in our mission is perhaps the most exciting. Read all about it here:
Finding a cure for Crohn’s Disease is a goal that has so far eluded doctors and medical researchers the world over. This is perhaps because of the complex set of conditions that are believed to give rise to the condition.
Crohn’s disease is an inflammatory bowel disease or “IBD” that can affect any part of the sufferer’s gastro-intestinal tract (from mouth right through to rectum) and can even cause inflammation of the skin, joints and eyes.
Crohn’s was previously thought to be an “Auto Immune” condition, where the body’s immune system mistakenly attacks its own tissues as it would an infection. However, understanding of the disease has increased in recent years and it is now thought to be an combination of inherited susceptibility to the condition and some, as yet unidentified, microbial infection.
In order to have any hope of curing Crohn’s disease, researchers first had to understand which genes might be responsible for a person’s susceptibility to the condition. Cure Crohn’s and Colitis funded one of the first research studies to successfully identify genes responsible for Crohn’s susceptibility. This ground-breaking research continues to be built upon by followup studies all over the world, developing an ever more detailed picture of the inherited traits that increase susceptibility to different kinds of inflammatory bowel disease.
Although this research shows incredible progress towards understanding and ultimately curing Crohn’s disease, it is still only the first piece of the puzzle. The next step is to understand why some people who might have the same genetic susceptibility will develop the disease, where others do not: Looking, in other words, for the external “trigger” for Crohn’s Disease.
The best hope for finding this trigger lies in the small country of Scotland. This country is perfect for this research because the large variety of races and genetic types that make up its population are evenly distributed throughout the country, yet the rates of Crohn’s Disease and Ulcerative Colitis are not – with marked concentrations of sufferers in certain areas.
Still more ideal from a research perspective, the whole of Scotland is covered by a single medical system, with information on every single Crohn’s patient being shared freely between its five main teaching hospitals.
These two sets of conditions exist nowhere else in the world, making it the ideal focus for discovering what lifestyle, environmental or medical differences are making one part of the population more likely to develop Crohn’s disease, while another is not. This is by far the most likely environment for finally answering the question, what causes Crohn’s disease and therefore how it can be cured.
Cure Crohn’s and Colitis have dedicated itself to funding this vital research. Using our simple approach, 100% of the funds we raise go directly towards funding research of this kind in Scotland.
All our staff are unpaid volunteers, many of whom have Crohn’s disease or a friend or family member suffering from IBD – this means we are just as motivated as you to create a solution to this painful and debilitating condition and curing Crohn’s Disease once and for all.